When the DNA results are not what was expected… The question came in again this past week, as it has so many times in recent years. A genealogist had asked others in the family to test to further the genealogist’s own research. When the results came in, well, they…
Resorce: Mark Orwig post access April 30, 2018, www.smarterhobby.com
Follow the link below.
(Correction) Resource: www.gedmatch.com access April 30, 2018
Presented as written.
April 28, 2018 We now have facility to allow users to delete their registration/profile and associated DNA and GEDCOM resources. If you are interested in how to use this facility Click here to find more information.
Deletion of Registration/Profile
We now have a facility to allow a user to delete their Profile/Registration along with all of their DNA resources (ie kits they have uploaded), GEDCOM resources (ie family trees) AND their login profile (ie user login) from the current database used by www.gedmatch.com
This deletion will be permanate and cannot be undone.
- You can access this facility under the “Your Log-in Profile” section with the link “View/Change/Delete your profile (password, email, groups)”.
- Click on the right tab labeled “Profile/Registration Deletion”.
- You will see DNA and GEDCOM resources and a place to verify your password at the bottom of the page.
- The next page is the final warning where you can click the delete button.
- You will then see DNA and GEDCOM resources as they are deleted – you can then click continue and will be logged out and directed to the login page.
- At this point your Profile/Registration and all resources are either deleted or scheduled for deletion.
April 27, 2018 To correct a BIG misunderstanding, we do not show any person’s DNA on GEDmatch. We only show manipulations of data such as DNA matches
April 27, 2018 We understand that the GEDmatch database was used to help identify the Golden State Killer. Although we were not approached by law enforcement or anyone else about this case or about the DNA, it has always been GEDmatch�s policy to inform users that the database could be used for other uses, as set forth in the Site Policy ( linked to the login page and https://www.gedmatch.com/policy.php). While the database was created for genealogical research, it is important that GEDmatch participants understand the possible uses of their DNA, including identification of relatives that have committed crimes or were victims of crimes. If you are concerned about non-genealogical uses of your DNA, you should not upload your DNA to the database and/or you should remove DNA that has already been uploaded.
It is amazing to me the number of genealogists who have stepped forward with some position and lack of confidence in Gedmatch. I do not subscribe to that line of thinking. What the media is not sharing is the platform used by Gedmatch to assist Law Enforcement. The application was built by Gedmatch and to be upfront, many testing companies were asked to help. Gedmatch is a very small company compared to FTDNS, 23andMe, and Ancestry.
Forensic genetic genealogist looked at the data provided by Gedmatch using a different Gedmatch tool. They found matches and used an interpretive pedigree process to isolate a potential suspect. Next was the collection of information to verify their conclusions.
This tool has nothing to do with the database housed on Gedmatch. At this point, I need to say I am reviewing the process. I still support Gedmatch, without the tools, it offers I would not have located and or discovered so many many relatives. Genetic or ancestors or distance cousins.
The errors and omissions set the stage for misunderstanding by news outlets and those in the genetic genealogy field of study for reasons abundant. To get noticed, recognized, accolades, see me.
The truth, Gedmatch provided no names but the data, it was Law Enforcement responsibility to determine the usefulness of the data. Once the determination was made and data numbers isolated, they could get a warrant to get the information release. They had a sample as a point of reference, not some random look in Gedmatch database. Do not believe all that you read, I can for once say “false news or fake news”. Ask questions before you leap to conclusions, be a true genealogist or genetic genealogist and follow investigative protocol.
For further reading, I recommend Shannon Christmas blog: https://www.facebook.com/throughthetreesblog/?hc_ref=ARTKHq0LewqcBPsoSXfNXkwwSv3yVqeChJ9gBRWNADDYOWeky903CJnST49w3R5A1As&fref=nf&hc_location=group
This dna visualization was created by Mike Toogood in the UK. Still working on the software for my own genealogy. Enjoy!
Join the dots today!
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- EASY AND SIMPLE – ‘Ever played join the dots … you can use visualisation.
- ARTISTIC – The pictures you produce are pleasing – there is no right or wrong way.
- MEANINGFULNESS – Layout the information in a way that looks meaningful to you.
What is DNADNA?
Join the dots for grown up Genealogists!
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- A VISUALISATION SYSTEM Network Analysis pictures can be used to understand complex systems.
- NET GRAPHS ARE IDEAL Understand links between distant DNA cousins.
- A DATA PRE PROCESSOR DNADNA uses logic and simple rules to prune and select the most genealogically relevant bits from the vast amount of data that is now available as more people DNA test.
- MATERNAL/PATERNAL/BOTH INFERENCE ENGINE DNADNA can infer likely relationships from known ones and color your graph accordingly.
By NICHOLAS ST. FLEUR JAN. 25, 2018
Access: The New York Times and The Times of Israel Jan. 25, 2018
This article changes a lot of our current genetic beliefs. It is my opinion, that the new data may verify my thoughts of what happened to the very first known haplogroup L0(A haplogroup is a genetic population group of people who share a common ancestor on the patriline or the matriline. Haplogroups are assigned letters of the alphabet, and refinements consist of additional number and letter combinations.) Dec 28, 2017
I have often written extensively about the Adams and Eves that existed long ago. Often getting negative reactions, silent and challenges to my beliefs. Interest in scientific, anthropological findings clearly researched and shared with other professionals worldwide. Again, I ask that you the reader keep an open mind. Just as anything else in this world, things change as we continue to dig and discover using the best anthropological and genetic tools available. It will be years before we can say for sure, that this is the missing L0 group who are the original men and women of Africa. For sure they are apart of the L0-L6 haplogroup of men and women of Africa. These groups migrated out of Africa over a long period of time, developing mutations such as skin, eye and hair color.
*All DNA testing companies have always used a Eurasian model with there algorithms. It is like a plague to use Africans in their models, which is a bias towards one group as opposed to an another. There are models that take into account African populations with significant results. ( dnatestedafrican.org) strongly suggest a full sequence maternal test if you can afford it or the next lowest which is 67 markers. Testing below YDNA 111 markers paternal is not worth your money but if you can at least test at 67 markers that is great. I do not challenge religious biblical ideology. That is an area that I have no expertise.
Adult ADHD: An imbalance between the online and offline brain (https://www.genome.gov/27569602/2017-news-feature-adult-adhd-an-imbalance-between-the-online-and-offline-brain/?utm_source=NHGRI+Email+Updates&utm_campaign=5b96bdbf21-Skin+Pigmentation+publications&utm_medium=email&utm_term=0_3d227b0341-5b96bdbf21-118937769)
By Jeannine Mjoseth (mailto:Jeannine.Mjoseth@nih.gov)
November 7, 2017
A new study by researchers at the National Human Genome Institute (NHGRI) examined why some people grow out of childhood attention deficit hyperactivity disorder (ADHD), while others continue to have symptoms into adulthood. They discovered that adults with ADHD persisting from childhood partly lose the usual balance of connections between brain networks that control action and those that control daydreaming or introspecting. Researchers have argued that this imbalance – between the brain “online” and the brain “offline”- might account for the lapses of attention that are found in ADHD. By contrast, adults who had “grown out” of their childhood ADHD, did not show such a loss of balanced brain activity, according to findings published October 31, 2017, in The Proceedings of the National Academy of Science (PNAS).
“We hope to understand the mechanisms that explain why some people outgrow ADHD and other do not,” said Philip Shaw, B.M.B.Ch., Ph.D., senior author and an investigator in NHGRI’s Social and Behavioral Research Branch (https://www.genome.gov/11508935/Social-and-Behavioral-Research-Branch/Social-and-Behavioral-Research-Branch/Social-and-Behavioral-Research-Branch?utm_source=NHGRI+Email+Updates&utm_campaign=5b96bdbf21-Skin+Pigmentation+publications&utm_medium=email&utm_term=0_3d227b0341-5b96bdbf21-118937769) . “If we can understand why some people can recover from ADHD, we also might be able to apply this knowledge to other neuro-developmental conditions like learning disabilities or problems with social interaction.”
ADHD (https://www.nimh.nih.gov/health/topics/attention-deficit-hyperactivity-disorder-adhd/index.shtml?utm_source=NHGRI+Email+Updates&utm_campaign=5b96bdbf21-Skin+Pigmentation+publications&utm_medium=email&utm_term=0_3d227b0341-5b96bdbf21-118937769) is a heritable and treatable brain disorder marked by inattention and/or hyperactivity-impulsivity that can cause great difficulties with impulse control, attention span in school, social situations and the workplace. Around 20 to 30 percent of people with ADHD retain the full syndrome as young adults and about 50 percent show partial, though not complete remission.
The researchers looked at brain function in 205 adult participants: 101 participants had been diagnosed with childhood ADHD and 104 subjects never had ADHD. They looked at changes in the brain’s oxygen levels to determine the location of brain networks using functional magnetic resonance imaging (fMRI) (mailto:http://fmri.ucsd.edu/Research/whatisfmri.html) , and they studied the different levels of neuronal activity that by looking at the brain’s magnetic fields using magnetoencephalography (mailto:http://ilabs.washington.edu/what-magnetoencephalography-meg) .
Regardless of the type of brain imaging used, the researchers found that adults who had inattentive symptoms persisting from childhood lost the usual balance of connections between the online and offline brain networks. Specifically, a network that is prominent when a person is introspective is usually switched off when a person engages in tasks. This balance was partly lost in the adults with persistent inattention. By contrast, this pattern of connections between brain networks in adults who outgrew ADHD looked very similar to the adults who never had ADHD. These findings support the theory that among individuals who recover from ADHD, there is a childhood disruption to brain function that corrects itself by adulthood.
“Most adults have a balance between the online, task-oriented brain and the offline, day-dreaming brain, but we found that’s not the case for adults whose ADHD persists,” said Gustavo Sudre, Ph.D., study co-author and postdoctoral research fellow in Dr. Shaw’s lab. “We found that adults who recovered from ADHD had a very similar balance of online and offline brains to those who never had ADHD.”
NHGRI’s investment in this type of high impact, longitudinal research and the participants’ long-term commitment to ADHD research make studies like this possible.
“We first met these individuals at the National Institutes of Health Clinical Center when they were eight years old,” Dr. Shaw said. “They are so committed to ADHD research that they have kept coming back for 14 years. It’s great to see so many of the children who had severe ADHD grow into adults who are managing very well.”
In the next step of their research, Drs. Shaw and Gustavo will collaborate with an international ADHD research consortium to find genes associated with the disrupted brain networks.
Read the study
Sudre G, Szekely E, Sharp W, Kasparek S, Shaw P. Multimodal mapping of the brain’s functional connectivity and the adult outcome of attention deficit hyperactivity disorder (http://www.pnas.org/content/114/44/11787.full?utm_source=NHGRI+Email+Updates&utm_campaign=5b96bdbf21-Skin+Pigmentation+publications&utm_medium=email&utm_term=0_3d227b0341-5b96bdbf21-118937769) . PNAS, October 31, 2017.
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